The meeting was organized by Simon Rabkin in beautiful Vancouver, and focused on global cardiovascular risk including diabetes mellitus, obesity, hyperlipidemia, and other risk factors associated with hypertension and cardiovascular disease, which are the major causes of death and disability across the world. The ISH 2010 meeting brought together over 2500 registrants from over 30 countries. The program was all encompassing including molecular and cellular science, clinical medicine, and population and health policy. ISH 2010 was held in conjunction with the annual meeting of the Canadian Hypertension Society, which has long been a very strong supporter and active Forum member of the ISH. Many special symposia, breakfast workshops, round table discussions and current guideline sessions enriched the program. The main events of the meeting were The ISH Forum meeting and The Bridging the Gaps Symposium.